Not masked. Not temporary. Measured and verified in a peer-reviewed clinical trial.
Less buildup. Healthier gum tissue. You will see it before the vet brings it up.
Even the picky ones. The beef bone broth base makes sure of it.
Source: Clinical trial · Animals journal · PubMed indexed · 2025
How It Works
DE-01 contains a clinically studied postbiotic that rebalances your dog's oral microbiome — the real source of bad breath. Instead of masking odors, it targets the bacteria causing them at the gum line. Most dog parents notice a meaningful difference within the first 7 days.
Yes. The postbiotic in DE-01 disrupts the biofilms that plaque and tartar build on. It won't dissolve heavy calculus overnight, but consistent daily use typically shows visible improvement in plaque accumulation and gum health around weeks 4–6.
Dental chews work by mechanical abrasion — the chewing physically scrapes the tooth surface, but only on the outer face. They don't reach below the gum line, between teeth, or into the oral microbiome. DE-01's postbiotic works biologically, targeting the bacteria that cause plaque, tartar, and bad breath at the source — while your dog eats their regular meal.
That's exactly what it's designed for. By keeping the oral microbiome balanced daily, you're stopping the bacterial buildup that leads to plaque, tartar, and gum disease before it starts. Think of it like brushing — the benefit compounds over time. Dogs who use it consistently tend to get much cleaner vet checks.
Using DE-01
Once daily, sprinkled over your dog's regular food. That's it — 10 seconds, same time every day.
Most dog parents notice fresher breath within the first week. Visible improvement in plaque and whitening typically shows up around weeks 4–6 of daily use. The 90-day mark is where the full transformation is most dramatic — cleaner teeth, healthier gums, and a noticeably fresher mouth at the vet.
Almost universally, yes. The formula is made with grass-fed beef bone broth and liver, so most dogs eat it right up. Even picky eaters tend to have no issues with this one.
Daily, ongoing — just like brushing. The benefit comes from consistency. Once your dog's oral health improves, daily use keeps it there and prevents the bacterial buildup from returning.
Absolutely. Sprinkle the scoop over whatever your dog is eating — kibble, wet food, raw, homemade, or stirred into bone broth. The key is that your dog consumes it with their meal.
Safety & Ingredients
The active ingredient is our clinically studied postbiotic dental strain. The formula also contains grass-fed beef bone broth and liver for palatability. All ingredients are human-grade — no artificial additives, no fillers, no synthetic preservatives. The full ingredient list is printed on every jar.
Yes, though we recommend waiting until your puppy has finished teething — typically around 6–7 months. After that, the daily routine is appropriate for dogs of any age.
Proudly made in the USA. GentlePaws DE-01 is manufactured in an FDA-registered facility using human-grade ingredients. Every batch is held to the highest quality and safety standards before it ships to your door.